Description

Ethyl 2-Butynoate is a versatile alkyne ester building block, valued for its reactive triple bond and ester functionality. This compound is essential for organic synthesis, enabling the construction of complex molecular frameworks through reactions like Sonogashira coupling and Michael additions. It is primarily used by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries to develop new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex heterocycles and bioactive molecules, particularly in anticancer and antiviral research.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its reactivity to create new active compounds.
• Organic Synthesis Building Block: Employed in Sonogashira cross-coupling, Michael addition, and [2+2] cycloaddition reactions to introduce acetylene units.
• Material Science Research: Serves as a monomer or precursor in the development of polymers and advanced materials with specific optical or electronic properties.
• Flavor & Fragrance Chemistry: Acts as a precursor for synthesizing specific esters and unsaturated compounds that contribute to complex aroma profiles.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for methodology development and exploring new synthetic pathways.

Basic Information

Product Name	Ethyl 2-Butynoate
CAS No.	4341-76-8
Molecular Formula	C6H8O2
Molecular Weight	112.13 g/mol
Synonyms	Ethyl but-2-ynoate; 2-Butynoic acid ethyl ester; Ethyl tetrolate; Ethyl acetylene carboxylate; Ethyl 2-butynate; Ethyl propiolate (related but distinct); But-2-ynoic acid ethyl ester
EINECS	224-413-9

Quality Control

Our Ethyl 2-Butynoate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, keep away from heat, sparks, and open flames. Ensure containers are kept tightly sealed when not in use to prevent evaporation and potential contamination.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Refractive Index (n20D)	1.420 - 1.430
Density (g/mL at 20°C)	0.950 - 0.980
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.