Description

7-Methyl-1,6-dioxaspiro[4.4]nonane-2-acetic acid is a specialized spirocyclic compound featuring a unique oxaspiro structure integrated with an acetic acid moiety, making it a valuable chiral building block and intermediate in advanced organic synthesis. Its complex, rigid framework is prized for constructing molecules with specific three-dimensional architectures, which is critical for modulating biological activity and physical properties in target compounds. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and fragrance industries, where precise stereochemistry and functional group compatibility are paramount.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drugs.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its spirocyclic core can contribute to improved efficacy and environmental profile.
• Fragrance & Flavor Chemistry: Acts as a building block for creating complex, musky, or woody odorants due to its constrained bicyclic ether structure.
• Material Science Research: Investigated as a monomer or additive for synthesizing polymers with unique thermal or mechanical properties.
• Asymmetric Catalysis: Employed as a ligand precursor or a chiral scaffold in the development of catalysts for stereoselective reactions.
• Academic & R&D Laboratories: Utilized in methodological studies and the discovery of new synthetic routes involving spirocyclic compounds.

Basic Information

Product Name	7-Methyl-1,6-dioxaspiro[4.4]nonane-2-acetic acid
CAS No.	4316-49-8
Molecular Formula	C11H16O4
Molecular Weight	212.24 g/mol
Synonyms	7-Methyl-1,6-dioxaspiro[4.4]nonane-2-acetic acid; 2-Acetic acid-7-methyl-1,6-dioxaspiro[4.4]nonane; 7-Methyl-1,6-dioxaspiro[4.4]nonane-2-acetic acid; 1,6-Dioxaspiro[4.4]nonane-2-acetic acid, 7-methyl-; (7-Methyl-1,6-dioxaspiro[4.4]nonan-2-yl)acetic acid
EINECS	Contact for details

Quality Control

Every batch of 7-Methyl-1,6-dioxaspiro[4.4]nonane-2-acetic acid is manufactured under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency meet the exacting standards required for synthetic intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 96.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.