Description

5-Butyl-5-Ethyl-1-Methylbarbituric Acid is a synthetic barbiturate derivative, a class of compounds historically significant in medicinal chemistry. Its precise molecular structure makes it a valuable key intermediate and reference standard for pharmaceutical research and analytical development. This compound is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in the synthesis or study of central nervous system (CNS) active agents and their metabolic pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of specialized barbiturate analogs and related heterocyclic compounds for research purposes.
• Reference Standard: Used as a high-purity analytical standard in method development and quality control for HPLC, GC, or LC-MS assays in pharmaceutical analysis.
• Biochemical Research: Employed in studies investigating the structure-activity relationships (SAR) of barbiturates and their interaction with biological targets like GABAA receptors.
• Metabolite Synthesis: Utilized in the preparation of potential drug metabolites for pharmacokinetic and toxicological studies.
• Chemical Standard: Provides a certified material for calibrating analytical instrumentation and verifying compound identity in chemical inventories.

Basic Information

Product Name	5-Butyl-5-Ethyl-1-Methylbarbituric Acid
CAS No.	4283-71-0
Molecular Formula	C11H18N2O3
Molecular Weight	226.27 g/mol
Synonyms	5-Ethyl-5-butyl-1-methylbarbituric acid; 1-Methyl-5-butyl-5-ethylbarbituric acid; 5-Butyl-5-ethyl-1-methyl-2,4,6(1H,3H,5H)-pyrimidinetrione; Butethal, 1-Methyl Derivative; NSC 401565
EINECS	Contact for details

Quality Control

Our 5-Butyl-5-Ethyl-1-Methylbarbituric Acid is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing specific results for assay, related substances, and other critical parameters is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.