Description

n-A-Cbz-L-Lysine p-Nitrophenyl Ester is a specialized, activated amino acid derivative used as a key building block in peptide synthesis. This compound matters for its role as a protected lysine precursor, enabling the controlled, sequential formation of peptide bonds in complex molecular assemblies. It is primarily needed by researchers and manufacturers in the pharmaceutical and biotechnology industries for the development of novel peptide-based therapeutics, diagnostics, and research reagents.

Application

• Solid-Phase Peptide Synthesis (SPPS): As an activated ester for the efficient incorporation of Cbz-protected lysine residues into peptide chains.
• Solution-Phase Peptide Synthesis: Used in classical coupling reactions for the synthesis of specific peptide fragments and small oligopeptides.
• Bioconjugation: A reagent for attaching peptide sequences or lysine moieties to other biomolecules, surfaces, or carrier proteins.
• Pharmaceutical Intermediate: Critical building block in the research and development of peptide drugs, including hormone analogs and enzyme inhibitors.
• Chemical Biology Probes: Used to create labeled or modified peptides for studying protein-protein interactions and cellular processes.
• Material Science: Potential monomer for creating functionalized polymers with peptide side chains for specialized applications.

Basic Information

Product Name	n-A-Cbz-L-Lysine p-Nitrophenyl Ester
CAS No.	4272-71-3
Molecular Formula	C20H23N3O6
Molecular Weight	401.42 g/mol
Synonyms	Nα-Carbobenzoxy-L-lysine p-nitrophenyl ester; Nα-Cbz-L-lysine 4-nitrophenyl ester; Nα-Z-L-lysine ONp; (S)-2-(((Benzyloxy)carbonyl)amino)-6-((4-nitrophenoxy)carbonyl)amino)hexanoic acid; Z-L-Lys-ONp; Cbz-L-Lysine pNP ester; N-Carbobenzyloxy-L-lysine p-nitrophenyl ester; Nα-CBZ-L-Lysine p-nitrophenyl ester
EINECS	Contact for details

Quality Control

Our n-A-Cbz-L-Lysine p-Nitrophenyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via spectroscopic methods. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C to -10°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent hydrolysis of the active ester group. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.