Description

3-[3-[Bis(2-Chloroethyl)Amino]Phenyl]Propanoic Acid is a specialized nitrogen mustard derivative with a carboxylic acid functional group. This molecular structure makes it a valuable chemical intermediate for the synthesis of more complex bioactive compounds. It is primarily sought by pharmaceutical research and development organizations, as well as fine chemical manufacturers engaged in producing targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of potential anticancer agents and other targeted therapeutics.
• Bioconjugation & Prodrug Development: The carboxylic acid moiety allows for conjugation to carriers, antibodies, or other molecules to create targeted drug delivery systems or prodrugs.
• Chemical Biology Research: Used as a tool compound in biochemical studies to investigate alkylation mechanisms and DNA interaction studies.
• Fine Chemical Synthesis: Serves as a precursor for creating libraries of novel compounds in medicinal chemistry for high-throughput screening.
• Academic & Institutional Research: Employed in university and government labs for fundamental research in oncology and drug mechanism of action.

Basic Information

Product Name	3-[3-[Bis(2-Chloroethyl)Amino]Phenyl]Propanoic Acid
CAS No.	4252-25-9
Molecular Formula	C₁₅H₂₀Cl₂NO₂
Molecular Weight	325.23 g/mol
Synonyms	3-[3-[Bis(2-chloroethyl)amino]phenyl]propionic acid; NSC 82116; Phenylpropanoic acid, 3-[bis(2-chloroethyl)amino]-; 3-(3-(Bis(2-chloroethyl)amino)phenyl)propanoic acid; β-[3-[Bis(2-chloroethyl)amino]phenyl]propionic acid; 3-(3-(Bis(chloroethyl)amino)phenyl)propanoic acid; Chlorambucil Impurity; Nitrogen Mustard Phenylpropanoic Acid Derivative
EINECS	Contact for details

Quality Control

Our 3-[3-[Bis(2-Chloroethyl)Amino]Phenyl]Propanoic Acid is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and synthesis. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.