Description

2-Hydroxy-6-Ethylpyridine-3-Carbonitrile is a versatile pyridine derivative and a key heterocyclic building block in advanced organic synthesis. Its molecular structure, featuring both a hydroxyl and a nitrile group, makes it a valuable precursor for creating complex pharmacologically active molecules and functional materials. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in developing kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the development of organic electronic materials, such as components for OLEDs or conductive polymers, due to its electron-deficient pyridine ring.
• Chemical Research & Development: A versatile scaffold in medicinal and combinatorial chemistry for constructing diverse heterocyclic libraries for high-throughput screening.

Basic Information

Product Name	2-Hydroxy-6-Ethylpyridine-3-Carbonitrile
CAS No.	4241-20-7
Molecular Formula	C8H8N2O
Molecular Weight	148.16 g/mol
Synonyms	6-Ethyl-2-hydroxynicotinonitrile; 3-Cyano-6-ethyl-2-pyridinol; 2-Pyridinol, 3-cyano-6-ethyl-; 6-Ethyl-2-hydroxy-3-cyanopyridine; 2-Hydroxy-6-ethyl-3-cyanopyridine; 6-Ethyl-2-oxo-1,2-dihydropyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-6-Ethylpyridine-3-Carbonitrile is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.