Description

5-Chloro-2-Hydroxypyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a chloro substituent and a hydroxyl group, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with pyridine-based core structures.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides, where the chloropyridine moiety is a common bioactive component.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed coupling reactions and other catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, metal-organic frameworks (MOFs), and functional polymers.
• Chemical Research & Development: A fundamental building block for medicinal chemistry programs and the exploration of novel heterocyclic compounds.

Basic Information

Product Name	5-Chloro-2-Hydroxypyridine
CAS No.	4214-79-3
Molecular Formula	C5H4ClNO
Molecular Weight	129.54 g/mol
Synonyms	2-Hydroxy-5-chloropyridine; 5-Chloro-2-pyridinol; 5-Chloro-2(1H)-pyridinone; 5-Chloro-2-pyridone; 2-Pyridinol, 5-chloro-; NSC 403697; 5-Chloro-1H-pyridin-2-one
EINECS	224-158-3

Quality Control

Every batch of 5-Chloro-2-Hydroxypyridine is produced under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.