Description

1β-Methyl-19-Norpregn-4-Ene-3,20-Dione is a high-purity synthetic steroid intermediate of significant importance in pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel therapeutic agents, particularly in the field of endocrinology and hormone-related therapies. It is primarily sought after by pharmaceutical R&D laboratories, advanced academic research institutions, and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of advanced steroid-based Active Pharmaceutical Ingredients (APIs).
• Hormone Research: Used in academic and industrial laboratories for studying structure-activity relationships (SAR) of progestogenic and other hormonal compounds.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable manufacturing of complex steroid molecules.
• Biochemical Tool Compound: Utilized in vitro and in vivo studies to investigate steroid receptor interactions and metabolic pathways.

Basic Information

Product Name	1β-Methyl-19-Norpregn-4-Ene-3,20-Dione
CAS No.	4183-69-1
Molecular Formula	C₂₁H₃₀O₂
Molecular Weight	314.46 g/mol
Synonyms	1β-Methyl-19-nor-4-pregnene-3,20-dione; 1β-Methyl-19-norpregn-4-ene-3,20-dione; 19-Nor-1β-methylpregn-4-ene-3,20-dione; 1β-Methyl-19-norprogesterone; 1β-Methyl-19-norpregn-4-en-3,20-dione; NSC 113926; 1β-Methyl-19-nor-4-pregnene-3,20-dione
EINECS	Contact for details

Quality Control

Our 1β-Methyl-19-Norpregn-4-Ene-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled and stored accordingly to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.