Description

Terephthalic Acid Bis(Trimethylsilyl) Ester is a high-purity silylating reagent and a key protected intermediate in organic synthesis. This compound is valued for its role in introducing the trimethylsilyl (TMS) group, which serves to protect reactive functional groups, modify solubility, and facilitate analysis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing complex molecules and polymers.

Application

• Pharmaceutical Intermediate: Used as a protected monomer or building block in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Polymer & Material Science: Serves as a precursor or modifying agent in the production of specialty polyesters, polyamides, and silicon-containing polymers for high-performance materials.
• Analytical Derivatization: Employed to silylate carboxylic acids and other protic compounds in Gas Chromatography (GC) and Mass Spectrometry (MS) to improve volatility and detection.
• Agrochemical Synthesis: Acts as an intermediate in the manufacture of advanced herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Reagent: Provides a versatile method for protecting terephthalic acid derivatives during multi-step synthetic sequences, enabling selective reactions.
• Liquid Crystal & OLED Research: Utilized as a key raw material in the development of organic electronic materials and liquid crystal displays.

Basic Information

Product Name	Terephthalic Acid Bis(Trimethylsilyl) Ester
CAS No.	4147-84-6
Molecular Formula	C14H24O4Si2
Molecular Weight	312.51 g/mol
Synonyms	1,4-Benzenedicarboxylic Acid, Bis(trimethylsilyl) Ester; Bis(trimethylsilyl) Terephthalate; Terephthalic Acid Bis(trimethylsilyl) Ester; Terephthalic Acid, Di(trimethylsilyl) Ester; TMS-Terephthalate; Di-TMS Terephthalate; Trimethylsilyl Terephthalate; p-Phthalic Acid Bis(trimethylsilyl) Ester
EINECS	Contact for details

Quality Control

Our Terephthalic Acid Bis(Trimethylsilyl) Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets precise customer specifications and industry standards. Comprehensive Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis and maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.