Description

5-Bromo-4-Fluoro-2-Hydroxy-Benzoic Acid Methyl Ester is a high-purity, multi-functional chemical intermediate with significant synthetic utility. Its value lies in its versatile halogenated and esterified aromatic structure, which serves as a critical building block for the development of complex molecules. This compound is essential for research and production in the pharmaceutical and agrochemical industries, where it is used to synthesize active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobial compounds.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of its bromo-fluoro-hydroxy substitution pattern.
• Liquid Crystal & OLED Material Research: Used in the development of advanced organic electronic materials and liquid crystal displays (LCDs) due to its aromatic core and halogen substituents.
• Organic Synthesis & Catalysis: Serves as a versatile substrate in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a ligand precursor in organometallic chemistry.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments where halogen atoms enhance lightfastness and alter color properties.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic methodologies and compound libraries.

Basic Information

Item	Detail
Product Name	5-Bromo-4-Fluoro-2-Hydroxy-Benzoic Acid Methyl Ester
CAS No.	4133-72-6
Molecular Formula	C8H6BrFO3
Molecular Weight	249.04 g/mol
Synonyms	Methyl 5-Bromo-4-Fluoro-2-Hydroxybenzoate; 5-Bromo-4-Fluoro-2-Hydroxybenzoic Acid Methyl Ester; 2-Hydroxy-5-Bromo-4-Fluorobenzoic Acid Methyl Ester; Methyl 2-Hydroxy-5-Bromo-4-Fluorobenzoate; 4-Fluoro-5-Bromo-2-Hydroxybenzoic Acid Methyl Ester; 5-Bromo-4-Fluoro-2-Hydroxy Methyl Benzoate; 4133-72-6; Benzoic acid, 5-bromo-4-fluoro-2-hydroxy-, methyl ester
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Fluoro-2-Hydroxy-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP standards where applicable, ensuring reliability for your most critical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is light-sensitive (store away from light) and should be handled under inert conditions if prolonged exposure is anticipated to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.