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Methyl 2-O,3-O,4-O,6-o-Tetrakis(Trimethylsilyl)-α-D-Galactopyranoside CAS NO 4133-45-3
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CAS No.:4133-45-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Methyl 2-O,3-O,4-O,6-o-Tetrakis(Trimethylsilyl)-α-D-Galactopyranoside is a fully protected derivative of methyl α-D-galactopyranoside, where all hydroxyl groups are silylated with trimethylsilyl (TMS) groups. This modification is critical for its primary role as a key synthetic intermediate and protecting group strategy in complex carbohydrate and nucleoside chemistry. It is an essential building block for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for the synthesis of oligosaccharides, glycoconjugates, and other bioactive molecules where selective deprotection is required.
Application
- Glycosylation Reactions: Serves as a crucial glycosyl donor or acceptor intermediate in the synthesis of complex oligosaccharides and glycans.
- Pharmaceutical Intermediate: Used in the research and development of novel carbohydrate-based drugs, vaccines, and diagnostic agents.
- Protecting Group Chemistry: The TMS groups provide robust protection for hydroxyl functionalities, allowing for selective reactions at other sites on the sugar molecule.
- Glycoconjugate Synthesis: A foundational reagent for creating glycoproteins, glycolipids, and other biologically active conjugates.
- Chemical Biology Research: Employed in studies exploring carbohydrate-protein interactions, cell surface recognition, and signaling pathways.
- Standards and Reference Materials: Used as a high-purity analytical standard for method development and quality control in carbohydrate analysis.
Basic Information
| Product Name | Methyl 2-O,3-O,4-O,6-o-Tetrakis(Trimethylsilyl)-α-D-Galactopyranoside |
| CAS No. | 4133-45-3 |
| Molecular Formula | C19H46O6Si4 |
| Molecular Weight | 482.90 g/mol |
| Synonyms | Methyl α-D-galactopyranoside 2,3,4,6-tetrakis-O-(trimethylsilyl) ether; Methyl 2,3,4,6-Tetra-O-trimethylsilyl-α-D-galactopyranoside; α-D-Galactopyranoside, methyl 2,3,4,6-tetrakis-O-(trimethylsilyl)-; Methyl α-D-Galactopyranoside, per-O-trimethylsilyl; TMS-protected Methyl α-D-galactoside; Per-O-trimethylsilylated Methyl α-D-galactopyranoside |
| EINECS | Contact for details |
Quality Control
Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and stability. Certificates of Analysis (COA) detailing specific batch results are available upon request. We adhere to strict quality management protocols to ensure supply consistency and reliability for critical research and production applications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow viscous liquid or solid |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥ 95.0% |
| Purity (GC) | ≥ 97.0% |
| Water Content (KF) | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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