Description

Diphenylphosphinyl Azide is a versatile organophosphorus reagent primarily used as a key intermediate in the synthesis of complex molecules. Its value lies in its ability to facilitate the Curtius rearrangement and other azide-based transformations, enabling the efficient construction of amines, isocyanates, and heterocycles. This compound is essential for R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to build molecular complexity with high selectivity.

Application

• Pharmaceutical Intermediate: A crucial reagent for the synthesis of active pharmaceutical ingredients (APIs), particularly in the preparation of carbamates and ureas via Curtius rearrangement.
• Peptide Mimetics & Bioconjugation: Used in the synthesis of peptide analogs and for introducing azide functional groups into biomolecules for click chemistry applications.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with specific amine or isocyanate functionalities.
• Material Science & Polymer Chemistry: Employed in the production of specialty polymers, polyurethanes, and functional materials that require azide or isocyanate cross-linking agents.
• Organic Synthesis Reagent: Facilitates various name reactions and is used in laboratory-scale and pilot-plant synthesis of complex organic compounds.

Basic Information

Product Name	Diphenylphosphinyl Azide
CAS No.	4129-17-3
Molecular Formula	C12H10N3OP
Molecular Weight	243.20 g/mol
Synonyms	Diphenylphosphinic Azide; Diphenylphosphoryl Azide (DPPA); Azidodiphenylphosphine Oxide; (Azidodiphenylphosphoryl)benzene; NSC 668348; Phosphinic Azide, Diphenyl-; P,P-Diphenylphosphinic Azide
EINECS	223-935-6

Quality Control

Our Diphenylphosphinyl Azide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.