Description

2-Amino5-Chloropyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both an amino and a chloro substituent, makes it a highly valuable intermediate for constructing complex molecular architectures. This compound is essential for research and production in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, particularly those targeting central nervous system disorders and infectious diseases.
• Agrochemical Synthesis: Used in the manufacture of advanced pesticides, herbicides, and fungicides due to its bioactive pyridine core.
• Ligand and Catalyst Preparation: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers and light-emitting compounds.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing specialized azo dyes and functional colorants.
• Custom Synthesis and R&D: A fundamental reagent for contract research organizations and academic laboratories exploring novel heterocyclic chemistry.

Basic Information

Product Name	2-Amino5-Chloropyridine
CAS No.	4124-74-8
Molecular Formula	C5H5ClN2
Molecular Weight	128.56 g/mol
Synonyms	2-Amino-5-chloropyridine; 5-Chloro-2-pyridinamine; 5-Chloro-2-aminopyridine; 2-Pyridinamine, 5-chloro-; 5-Chloropyridin-2-amine; NSC 401122; 2-Amino-5-chloropyridine (principal synonym)
EINECS	223-927-3

Quality Control

Our 2-Amino5-Chloropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment ensures the material is suitable for demanding applications in GMP-aligned synthesis and research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect purity and stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.