Description

D-Aspartic Acid, Bis(Phenylmethyl) Ester is a protected derivative of the non-essential amino acid D-aspartic acid, where the carboxylic acid groups are esterified with benzyl groups. This chemical modification is crucial for its primary role as a key chiral building block and synthetic intermediate in advanced organic synthesis. It is particularly valuable for researchers and manufacturers in the pharmaceutical and fine chemical industries who require high-purity, enantiomerically pure intermediates for the development of peptides, active pharmaceutical ingredients (APIs), and other complex organic molecules.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in the preparation of peptide fragments where the benzyl ester protecting groups can be selectively removed under specific conditions.
• Asymmetric Synthesis: Serves as a starting material or intermediate in catalytic asymmetric reactions to construct molecules with defined stereochemistry.
• Biochemical Research: Employed in studies of enzyme mechanisms, receptor binding, and metabolic pathways involving D-amino acids.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, catalysts, and ligands for chemical processes.
• Agrochemical Development: Potential intermediate in the research and synthesis of novel, chiral agrochemicals and plant growth regulators.

Basic Information

Product Name	D-Aspartic Acid, Bis(Phenylmethyl) Ester
CAS No.	4079-59-8
Molecular Formula	C18H19NO4
Molecular Weight	313.35 g/mol
Synonyms	D-Aspartic acid dibenzyl ester; Dibenzyl D-aspartate; (R)-2-Aminobutanedioic acid 1,4-dibenzyl ester; D-2-Aminosuccinic Acid Dibenzyl Ester; D-Aspartic Acid Dibenzyl Ester; Benzyl D-aspartate; (R)-Dibenzyl aspartate; H-D-Asp(OBzl)-OBzl
EINECS	Contact for details

Quality Control

Our D-Aspartic Acid, Bis(Phenylmethyl) Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure high chemical purity, enantiomeric excess, and consistent performance. We provide Certificates of Analysis (COA) with detailed results for parameters including assay, chiral purity (HPLC), and identification. Our quality systems support compliance with cGMP and ISO standards for pharmaceutical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee (D-isomer)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.