Description

trans-2,5-Dimethyl-1,3-Dioxolan-4-One is a high-purity, cyclic ester compound, also known as a dioxolanone. This specialty chemical is valued for its role as a versatile intermediate and building block in advanced organic synthesis. It is primarily sought after by research and development laboratories and industrial manufacturers in the pharmaceutical and fine chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of antiviral and cardiovascular drugs.
• Fine Chemical Synthesis: Used as a precursor for the preparation of complex natural products, flavors, and fragrances.
• Polymer Chemistry: Serves as a monomer or co-monomer for producing specialized biodegradable or functional polymers.
• Agrochemical Research: Employed in the development of novel herbicides and pesticides with specific stereochemical requirements.
• Academic & Industrial R&D: A valuable reagent in methodological chemistry research for studying ring-opening reactions and asymmetric synthesis.
• Ligand and Catalyst Preparation: Used in the synthesis of chiral ligands and organocatalysts for asymmetric catalysis.

Basic Information

Product Name	trans-2,5-Dimethyl-1,3-Dioxolan-4-One
CAS No.	4051-08-5
Molecular Formula	C5H8O3
Molecular Weight	116.12 g/mol
Synonyms	(4R,5S)-(-)-4,5-Dimethyl-1,3-dioxolan-4-one; (4S,5R)-(+)-4,5-Dimethyl-1,3-dioxolan-4-one; 2,5-Dimethyl-1,3-dioxolan-4-one; D(-)-2,3-Isopropylidene-D-glyceric acid γ-lactone; L(+)-2,3-Isopropylidene-L-glyceric acid γ-lactone; trans-4,5-Dimethyl-1,3-dioxolan-4-one; Dioxolanone derivative
EINECS	223-749-8

Quality Control

Our trans-2,5-Dimethyl-1,3-Dioxolan-4-One is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) specifying identity, purity, and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% (specify isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.