Description

1,2,3,4-Tetra-o-Acetyl-β-D-Xylopyranose is a key protected monosaccharide derivative, widely used as a versatile chiral building block in organic synthesis. Its primary value lies in providing a stable, reactive intermediate for the controlled construction of complex carbohydrate structures and nucleoside analogs. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries, particularly for developing antiviral agents, enzyme inhibitors, and novel glycoconjugates. CAS No. 4049-33-6.

Application

• Pharmaceutical Intermediate: Critical starting material for the synthesis of nucleoside analogs with potential antiviral and anticancer activities.
• Glycochemistry Research: Serves as a protected xylose donor for the enzymatic or chemical synthesis of oligosaccharides, glycopeptides, and glycolipids.
• Prodrug Development: Used to create prodrug forms of therapeutic agents by masking hydroxyl groups, improving bioavailability and stability.
• Enzyme Inhibitor Synthesis: Building block for creating glycosidase and glycosyltransferase inhibitors, which are important in metabolic disease research.
• Fine Chemical Synthesis: Chiral precursor for the production of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Bioconjugation: Used to introduce carbohydrate moieties onto proteins, peptides, or other biomolecules for diagnostic and therapeutic applications.

Basic Information

Product Name	1,2,3,4-Tetra-o-Acetyl-β-D-Xylopyranose
CAS No.	4049-33-6
Molecular Formula	C13H18O9
Molecular Weight	318.28 g/mol
Synonyms	1,2,3,4-Tetra-O-acetyl-β-D-xylopyranose; β-D-Xylopyranose, 1,2,3,4-tetraacetate; Tetra-O-acetyl-β-D-xylopyranose; Acetylated β-D-xylose; Xylose tetraacetate; β-D-Xylose tetraacetate; 2,3,4-Tri-O-acetyl-α/β-D-xylopyranosyl acetate (mixture reference); Xylopyranose tetraacetate
EINECS	223-758-5

Quality Control

Our 1,2,3,4-Tetra-o-Acetyl-β-D-Xylopyranose is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and identity confirmation via IR and NMR spectroscopy. We provide Certificates of Analysis (COA) with each shipment, detailing all critical parameters to ensure compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can lead to hydrolysis of the acetyl groups. For long-term storage, consider using a desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	-20° to -24° (c=1 in CHCl₃)
Melting Point	128°C - 132°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.