Description

Nicotinoyl Azide is a versatile organic azide derivative of nicotinic acid, serving as a critical building block in advanced chemical synthesis. Its reactive azide group makes it a valuable precursor for generating nitrenes or participating in click chemistry reactions like the Staudinger ligation and copper-catalyzed azide-alkyne cycloaddition (CuAAC). This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to create novel molecular scaffolds, active pharmaceutical ingredients (APIs), and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those containing triazole or other heterocyclic structures via click chemistry.
• Agrochemical Research: Used in the development of new pesticides and herbicides by enabling the modular construction of complex molecules.
• Bioconjugation & Probe Synthesis: Facilitates the labeling of biomolecules (proteins, peptides, nucleic acids) for diagnostic assays and biochemical research.
• Polymer & Material Science: Acts as a cross-linking agent or functional monomer for creating specialty polymers with unique properties.
• Organic Synthesis Reagent: Employed in the generation of nitrenes for C-H amination and other insertion reactions to form new C-N bonds.
• Chemical Library Development: A valuable building block for combinatorial chemistry and high-throughput screening in drug discovery.

Basic Information

Product Name	Nicotinoyl Azide
CAS No.	4013-72-3
Molecular Formula	C6H4N4O
Molecular Weight	148.12 g/mol
Synonyms	3-Pyridinecarbonyl azide; Nicotinic acid azide; Nicotinyl azide; Pyridine-3-carbonyl azide; 3-Azidocarbonylpyridine; Isonicotinoyl azide (related isomer); 3-Carbamoylpyridine azide
EINECS	Contact for details

Quality Control

Every batch of Nicotinoyl Azide is manufactured and tested under strict quality management systems to ensure consistency and reliability for your critical applications. We provide comprehensive analytical data, including purity by HPLC, identity confirmation by FT-IR and NMR, and impurity profiling. A Certificate of Analysis (COA) is supplied with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and documentation excellence.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its light-sensitive nature and the general reactivity of organic azides, prolonged exposure to light, heat, or moisture should be avoided. Keep away from incompatible materials such as strong reducing agents and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.