Description

Pyridine-2-Carbonyl Azide is a versatile heterocyclic building block and reagent used in organic synthesis. This compound is valued for its role as a precursor to reactive intermediates, particularly in the synthesis of carbamates, ureas, and other nitrogen-containing heterocycles. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing carbamate or urea functionalities via Curtius rearrangement.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific nitrogen-based heterocyclic cores.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the production of specialty polymers and polyurethanes with tailored properties.
• Peptide Mimetics & Bioconjugation: Employed in the preparation of isocyanate derivatives for labeling biomolecules or creating peptide backbone modifications.
• Material Science Research: Utilized in the development of metal-organic frameworks (MOFs), covalent organic frameworks (COFs), and other advanced porous materials.
• Chemical Biology Probes: Acts as a precursor for photoaffinity labeling reagents and other tools used to study enzyme mechanisms and protein interactions.

Basic Information

Product Name	Pyridine-2-Carbonyl Azide
CAS No.	4013-71-2
Molecular Formula	C6H4N4O
Molecular Weight	148.12 g/mol
Synonyms	2-Pyridinecarbonyl Azide; Picolinoyl Azide; 2-Picolinoyl Azide; Azidocarbonylpyridine; Pyridine-2-carboxylic Acid Azide; 2-Azidocarbonylpyridine; Picolinic Acid Azide
EINECS	Contact for details

Quality Control

Our Pyridine-2-Carbonyl Azide is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized by comprehensive analytical techniques including NMR, HPLC, and IR spectroscopy. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its azide functionality and light-sensitive nature, prolonged exposure to heat, direct light, or strong mechanical shock should be avoided. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	48 - 52 °C
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.