Description

4-Hydroxypyridine-2,6-Dicarboxylic Acid is a versatile chelating agent and key organic intermediate with a dipicolinic acid core structure. This compound is valued for its ability to form stable complexes with various metal ions, making it crucial for applications requiring precise metal coordination. It is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting neurological pathways or acting as enzyme inhibitors.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators that require specific metal-chelating properties.
• Coordination Chemistry & Catalysis: Acts as a precursor for ligands in homogeneous catalysis and in the preparation of metal-organic frameworks (MOFs) for gas storage or separation.
• Analytical Reagent: Employed as a complexometric titrant or a standard in analytical methods for the determination of metal ion concentrations.
• Biochemical Research: Utilized in studies of enzyme mechanisms and metalloprotein modeling due to its structural similarity to natural chelators.
• Polymer Modification: Incorporated into polymer chains to impart metal-binding capabilities for creating functional materials like ion-exchange resins or sensors.

Basic Information

Product Name	4-Hydroxypyridine-2,6-Dicarboxylic Acid
CAS No.	499-51-4
Molecular Formula	C7H5NO5
Molecular Weight	183.12 g/mol
Synonyms	2,6-Dicarboxy-4-hydroxypyridine; 4-Hydroxydipicolinic Acid; Chelidamic Acid; 4-Pyridinol-2,6-dicarboxylic Acid; 2,6-Pyridinedicarboxylic acid, 4-hydroxy-; 4-Hydroxy-2,6-pyridinedicarboxylic Acid; 4-Hydroxypyridine-2,6-dicarboxylate
EINECS	207-881-5

Quality Control

Our 4-Hydroxypyridine-2,6-Dicarboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting key parameters such as assay, impurity profile, and residual solvents. Our quality commitment ensures the material is suitable for demanding applications in research and regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed immediately after use to prevent absorption of atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.