Description

1,2,3,6-Tetrahydro-Pyridine-2-Carboxylic Acid is a versatile heterocyclic building block and chiral synthon of significant importance in advanced organic synthesis. Its constrained piperidine-like structure makes it a valuable intermediate for constructing complex molecules, particularly in the pharmaceutical sector. This compound is primarily sought after by research institutions and manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of various drug candidates, particularly those targeting the central nervous system.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides due to its bioactive scaffold.
• Ligand and Catalyst Development: Serves as a backbone for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic and R&D: A valuable compound for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	1,2,3,6-Tetrahydro-Pyridine-2-Carboxylic Acid
CAS No.	498-98-6
Molecular Formula	C6H9NO2
Molecular Weight	127.14 g/mol
Synonyms	2-Piperidinecarboxylic acid, 1,2,3,6-tetrahydro-; 1,2,3,6-Tetrahydro-2-picolinic acid; δ³-Piperidine-2-carboxylic acid; 2-Carboxy-1,2,3,6-tetrahydropyridine; NSC 403697; 1,2,3,6-Tetrahydro-2-pyridinecarboxylic acid; (R/S)-1,2,3,6-Tetrahydro-2-pyridinecarboxylic acid
EINECS	207-879-3

Quality Control

Our 1,2,3,6-Tetrahydro-Pyridine-2-Carboxylic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing specific results for purity, residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.