Description

Chlornaphazine is a nitrogen mustard derivative and a bifunctional alkylating agent of significant historical and research interest. Its primary value lies in its role as a key reference compound in the study of chemotherapeutic agents and their mechanisms of action. This product is essential for researchers and developers in the pharmaceutical and life sciences sectors, particularly those focused on oncology research, chemical biology, and the development of novel therapeutic agents. We supply high-purity Chlornaphazine CAS NO 494-03-1 to support critical R&D and analytical applications globally.

Application

• Pharmaceutical Research & Development: Serves as a reference standard and active pharmaceutical ingredient (API) intermediate in oncology research.
• Chemical Biology Studies: Used to investigate alkylation mechanisms, DNA cross-linking, and the biochemical pathways of nitrogen mustard agents.
• Academic & Institutional Research: Employed in university and institutional laboratories for studies in medicinal chemistry, pharmacology, and toxicology.
• Analytical Standard: Utilized as a high-purity standard for method development, validation, and quality control (QC) in HPLC, GC-MS, and NMR analysis.
• Historical Compound Analysis: Provides a benchmark for comparative studies with newer generation chemotherapeutic agents.

Basic Information

Product Name	Chlornaphazine
CAS No.	494-03-1
Molecular Formula	C14H16Cl2N2
Molecular Weight	283.20 g/mol
Synonyms	Chlornaphazin; NSC-34462; CB 1048; N,N-Bis(2-chloroethyl)-2-naphthylamine; 2-Naphthylbis(2-chloroethyl)amine; Dichloren; R-48; Erysan
EINECS	207-791-8

Quality Control

Our Chlornaphazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assay by HPLC, and control of related substances. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with our rigorous in-house specifications. We support research and development with material traceability and documentation suitable for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.