Description

Artemisinin is a potent sesquiterpene lactone endoperoxide, a key active pharmaceutical ingredient (API) derived from the sweet wormwood plant, *Artemisia annua*. This compound serves as the crucial starting material for the semi-synthesis of more potent and bioavailable artemisinin-based combination therapies (ACTs), which are the first-line treatment for malaria as recommended by the World Health Organization. It is essential for pharmaceutical manufacturers, research institutions, and fine chemical suppliers engaged in the production of antimalarial drugs and the exploration of its potential in other therapeutic areas.

Application

• Pharmaceutical API Synthesis: Primary use as the starting material for the production of derivative antimalarial drugs such as artemether, artesunate, and dihydroartemisinin.
• Antimalarial Drug Formulation: Direct incorporation into formulations for Artemisinin-based Combination Therapies (ACTs), the global standard for *Plasmodium falciparum* malaria treatment.
• Biomedical Research: Investigation of its mechanisms of action, including its role in generating free radicals that target malaria parasites, and studies on potential resistance.
• Oncology Research: Exploration of artemisinin and its derivatives for potential anticancer properties, leveraging its selective cytotoxicity under certain conditions.
• Veterinary Pharmaceuticals: Development of treatments for parasitic infections in animals.
• Reference Standard: Serves as a high-purity chemical reference standard (CRS) for quality control and analytical testing in pharmacopeial (USP, EP) methods.

Basic Information

Product Name	Artemisinin
CAS No.	491-54-3
Molecular Formula	C15H22O5
Molecular Weight	282.33 g/mol
Synonyms	Qinghaosu; Artemisinine; (+)-Artemisinin; 3R,5aS,6R,8aS,9R,12S,12aR)-Octahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one; Arteamuin B; NSC 369397; WR 25605
EINECS	207-753-0

Quality Control

Our Artemisinin is produced and tested under a strict quality management system. It can be supplied to meet various pharmacopeial standards, including USP and EP monographs, ensuring suitability for pharmaceutical manufacturing. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We ensure traceability and compliance with relevant regulatory frameworks for active pharmaceutical ingredients (APIs).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The container must be kept tightly sealed to protect the product from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0% - 102.0%
Melting Point	151°C - 156°C
Specific Rotation	+75° to +78° (c=1, CHCl3)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.