Description

Butein CAS NO 487-52-5 is a naturally occurring chalcone derivative, a polyphenolic compound known for its distinctive yellow color and significant biological activity. This high-purity chemical is valued for its role as a key research compound and a potential active ingredient in advanced applications. It is primarily sought by researchers and manufacturers in the pharmaceutical, nutraceutical, and life science sectors for its promising therapeutic properties and as a reference standard.

Application

• Pharmaceutical Research & Development: Investigated for its anti-inflammatory, antioxidant, and potential anti-cancer properties in preclinical studies.
• Biochemical Research: Used as a specific inhibitor of protein tyrosine kinases and other enzymes to study cellular signaling pathways.
• Nutraceutical Formulation: Serves as a premium bioactive ingredient in advanced dietary supplements targeting oxidative stress.
• Cosmeceutical Applications: Incorporated into skincare formulations for its antioxidant and potential skin-brightening effects.
• Analytical Reference Standard: Employed as a high-purity standard in HPLC, LC-MS, and other analytical methods for quality control and quantification.
• Natural Product Chemistry: Used as a building block or intermediate in the synthesis of more complex natural product analogs.

Basic Information

Product Name	Butein
CAS No.	487-52-5
Molecular Formula	C15H12O5
Molecular Weight	272.25 g/mol
Synonyms	2',3,4,4'-Tetrahydroxychalcone; 3,4,2',4'-Tetrahydroxychalcone; (E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one; Butin; CI 1037; Buteine; Carthamin; Natural Yellow 11
EINECS	207-665-2

Quality Control

Our Butein is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC for purity, IR and MS for identification, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with our stringent specifications. We support research and GMP-grade requirements with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to prevent degradation. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to orange-yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0 %
Residue on Ignition	≤ 0.5 %
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.