Description

Forsythin is a high-purity, naturally derived lignan glycoside, also known as phillyrin, primarily extracted from the fruit of *Forsythia suspensa*. This compound serves as a key active pharmaceutical ingredient (API) and a critical reference standard for quality control in botanical and pharmaceutical manufacturing. It is essential for suppliers and manufacturers in the pharmaceutical, nutraceutical, and research sectors who require a reliable, high-quality source for product development and standardization.

Application

• As a reference standard for the HPLC/LC-MS identification and quantification of *Forsythia suspensa* extracts and related herbal products.
• As a key active pharmaceutical ingredient (API) in the formulation of traditional and modern herbal medicines targeting anti-inflammatory and antiviral applications.
• In nutraceutical and dietary supplement formulations, leveraging its bioactive properties for immune support products.
• For research and development in pharmacology and phytochemistry to study its mechanisms of action, bioavailability, and potential new therapeutic uses.
• In cosmeceutical applications, where its natural origin and bioactive profile are valued for skin health formulations.
• As a critical component in quality control (QC) laboratories to ensure batch-to-batch consistency and regulatory compliance of finished herbal products.

Basic Information

Product Name	Forsythin
CAS No.	487-41-2
Molecular Formula	C27H34O11
Molecular Weight	534.56 g/mol
Synonyms	Phillyrin; Forsythoside A Precursor; (+)-Phillyrin; Forsythin A; Ligustrin; Forsythiaside intermediate; 4-[(3S,4R,5S,6S)-4,5-Dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-2-methoxyphenyl (2R,3R)-3-(4-hydroxy-3-methoxyphenyl)oxirane-2-carboxylate
EINECS	207-664-8

Quality Control

Our Forsythin is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC and spectroscopic methods, to ensure it meets high-purity standards suitable for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Conforms to reference retention time
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.