Description

Artemisin CAS NO 481-05-0 is a naturally occurring sesquiterpene lactone endoperoxide, recognized as the primary bioactive precursor for the synthesis of potent antimalarial drugs. Its unique endoperoxide bridge is critical for generating free radicals that are lethal to *Plasmodium* parasites, making it a cornerstone compound in global pharmaceutical supply chains. This high-purity intermediate is essential for manufacturers in the pharmaceutical, research, and fine chemical sectors requiring a reliable source for producing artemisinin-based combination therapies (ACTs) and novel therapeutic agents.

Application

• Active Pharmaceutical Ingredient (API) Synthesis: Primary precursor for the semi-synthesis of artemisinin derivatives like artemether, artesunate, and dihydroartemisinin used in antimalarial medications.
• Pharmaceutical Research & Development: Key starting material for investigating new artemisinin-based therapies for malaria, cancer, and viral infections.
• Fine Chemical Intermediate: Used in organic synthesis to construct complex molecules leveraging its unique endoperoxide functionality.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical laboratories.
• Veterinary Pharmaceuticals: Employed in the development of antiparasitic treatments for animals.
• Natural Product Extraction & Isolation: Target compound for extraction and purification from *Artemisia annua* (sweet wormwood) plant sources.

Basic Information

Product Name	Artemisin
CAS No.	481-05-0
Molecular Formula	C15H22O5
Molecular Weight	282.33 g/mol
Synonyms	Artemisinin; Qinghaosu; Arteannuin; Artemisinine; 3R,5aS,6R,8aS,9R,12S,12aR)-Octahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one; (+)-Artemisinin; NSC 369397
EINECS	207-574-5

Quality Control

Our Artemisin is produced and tested under strict quality management systems to ensure it meets the rigorous standards required for pharmaceutical applications. We offer grades compliant with relevant pharmacopoeial monographs (e.g., USP, EP). Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, ensuring full traceability and regulatory support for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The container must be kept tightly sealed to protect the product from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0% - 102.0%
Melting Point	156°C - 158°C
Specific Rotation	+75° to +78° (c=1, CHCl3)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.