Description

16 Beta,17 β-Epoxy-1,3,5(10)-Estratrien-3-Ol is a high-purity steroidal epoxide derivative, serving as a critical advanced intermediate in organic synthesis. This compound matters for its role in the targeted synthesis of complex steroid-based molecules, offering researchers and manufacturers precise control over molecular architecture. It is primarily needed by the pharmaceutical and biotechnology industries for the research and development of novel therapeutic agents, including hormone modulators and other bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel steroidal drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or precursor in metabolic pathway studies and receptor binding assays.
• Hormone Analog Development: Serves as a core structure for creating new estrogen receptor modulators and related therapeutic candidates.
• Organic Synthesis: Valuable epoxide intermediate for introducing specific stereochemistry in complex multi-step synthetic routes.
• Academic & Contract Research: Employed in university and CRO laboratories for medicinal chemistry projects and method development.

Basic Information

Product Name	16 Beta,17 β-Epoxy-1,3,5(10)-Estratrien-3-Ol
CAS No.	472-57-1
Molecular Formula	C18H22O2
Molecular Weight	270.37 g/mol
Synonyms	16β,17β-Epoxyestradiol; 16β,17β-Epoxyestra-1,3,5(10)-triene-3,17β-diol; 16β,17β-Epoxy-3,17β-estradiol; 16β,17β-Epoxy-17β-estradiol; 16β,17β-Epoxyestra-1,3,5(10)-triene-3,17β-diol; Estra-1,3,5(10)-triene-3,16β,17β-triol, 16,17-epoxide; (16β,17β)-16,17-Epoxyestra-1,3,5(10)-triene-3,17-diol
EINECS	207-439-1

Quality Control

Our 16 Beta,17 β-Epoxy-1,3,5(10)-Estratrien-3-Ol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets exacting standards for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.