Description

Acetic Acid, 2,2,2-Trifluoro-, 1,1-Dimethylpropyl Ester is a specialized fluorinated ester compound, also known as 1,1-Dimethylpropyl 2,2,2-trifluoroacetate. This high-purity intermediate is valued for its unique trifluoroacetyl group, which imparts significant chemical stability and reactivity, making it a critical building block in advanced synthetic chemistry. It is primarily sought after by research and development laboratories and fine chemical manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring the introduction of a trifluoroacetate protecting group or a trifluoromethyl moiety to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atoms contribute to improved efficacy and environmental persistence.
• Organic Synthesis Reagent: Serves as a versatile trifluoroacetylating agent in academic and industrial research for modifying alcohols, amines, and other nucleophiles.
• Material Science Precursor: Employed in the development of specialty polymers and coatings that benefit from the incorporation of fluorine for enhanced thermal stability, chemical resistance, and low surface energy.
• Liquid Crystal & Electronic Chemicals: Acts as a precursor or intermediate in the manufacture of fluorinated compounds used in liquid crystal displays (LCDs) and other electronic materials.

Basic Information

Product Name	Acetic Acid, 2,2,2-Trifluoro-, 1,1-Dimethylpropyl Ester
CAS No.	461-73-4
Molecular Formula	C7H11F3O2
Molecular Weight	184.16 g/mol
Synonyms	1,1-Dimethylpropyl 2,2,2-trifluoroacetate; tert-Pentyl 2,2,2-trifluoroacetate; 2,2,2-Trifluoroacetic Acid 1,1-Dimethylpropyl Ester; 2,2,2-Trifluoroacetic Acid tert-Pentyl Ester; TFA tert-Pentyl Ester; 1,1-Dimethylpropyl Trifluoroacetate; tert-Amyl Trifluoroacetate
EINECS	Contact for details

Quality Control

Our Acetic Acid, 2,2,2-Trifluoro-, 1,1-Dimethylpropyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.360 - 1.380
Density (20°C)	1.10 - 1.20 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.