Description

2-Fluoroethylamine Hydrochloride is a versatile organofluorine building block essential for introducing the 2-fluoroethylamine moiety into complex molecules. This high-purity salt form offers enhanced stability and handling characteristics compared to the free base, making it a critical intermediate in advanced synthetic workflows. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorine-containing drugs for oncology, neurology, and antiviral applications.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the fluorine atom can enhance biological activity and environmental stability.
• Bioconjugation & Probe Development: Serves as a reagent for modifying biomolecules, peptides, and proteins to create fluorescent probes or targeted conjugates for diagnostic and research purposes.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and advanced materials where fluorine incorporation can alter physical properties like solubility, thermal stability, and surface energy.
• Chemical Biology & Medicinal Chemistry: A valuable scaffold in fragment-based drug discovery and for creating chemical libraries to explore structure-activity relationships (SAR).

Basic Information

Product Name	2-Fluoroethylamine Hydrochloride
CAS No.	460-08-2
Molecular Formula	C₂H₇ClFN
Molecular Weight	99.53 g/mol
Synonyms	2-Fluoroethanamine Hydrochloride; 2-Fluoroethylammonium Chloride; 1-Amino-2-fluoroethane Hydrochloride; 2-Fluoro-1-ethylamine Hydrochloride; Monofluoroethylamine HCl; FEA HCl; (2-Fluoroethyl)amine Hydrochloride; β-Fluoroethylamine Hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Fluoroethylamine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) that include results from HPLC, NMR, and titration methods, confirming compliance with customer specifications and industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.