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Methyl 6-Fluoropicolinate CAS NO 455-71-0


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CAS No.:455-71-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Methyl 6-Fluoropicolinate is a high-purity fluorinated heterocyclic building block essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of a fluorine atom can significantly alter biological activity and metabolic stability. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

  • Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
  • Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluoropicolinate moiety contributes to efficacy and environmental profile.
  • Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in catalytic processes and material science applications.
  • Chemical Research: Employed in academic and industrial R&D for exploring new fluorination reactions and heterocyclic chemistry.
  • Fine Chemical Production: Acts as an intermediate in the multi-step synthesis of other high-value fluorinated fine chemicals and specialty materials.

Basic Information

Product Name Methyl 6-Fluoropicolinate
CAS No. 455-71-0
Molecular Formula C7H6FNO2
Molecular Weight 155.13 g/mol
Synonyms 6-Fluoropicolinic Acid Methyl Ester; Methyl 6-Fluoropyridine-2-carboxylate; 2-Pyridinecarboxylic Acid, 6-Fluoro-, Methyl Ester; 6-Fluoro-2-pyridinecarboxylic Acid Methyl Ester; Methyl 6-Fluoro-2-pyridinecarboxylate; 6-Fluoropicolinate Methyl Ester; Methyl 6-Fluoropicolate
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Quality Control

Our Methyl 6-Fluoropicolinate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical and agrochemical end-users.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong bases and oxidizing agents.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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