Description

2,4-Bis(Trifluoromethyl)Pyridine is a high-value fluorinated pyridine derivative, distinguished by its two electron-withdrawing trifluoromethyl groups which impart unique reactivity and stability. This compound is a critical building block in advanced organic synthesis, enabling the introduction of fluorine atoms to fine-tune the properties of target molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors seeking to develop novel active ingredients and high-performance polymers.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance bioavailability and environmental stability.
• Ligand and Catalyst Development: Acts as a precursor for nitrogen-containing ligands in transition metal catalysis, facilitating challenging cross-coupling and fluorination reactions.
• Functional Material Precursor: Employed in the synthesis of specialty polymers, liquid crystals, and electronic materials requiring specific dielectric and surface properties.
• Organic Synthesis Building Block: Utilized in medicinal and process chemistry for nucleophilic substitution and metal-halogen exchange reactions to construct complex heterocyclic systems.

Basic Information

Product Name	2,4-Bis(Trifluoromethyl)Pyridine
CAS No.	454-99-9
Molecular Formula	C7H3F6N
Molecular Weight	215.10 g/mol
Synonyms	2,4-Bis(trifluoromethyl)pyridine; α,α,α,α',α',α'-Hexafluoro-2,4-lutidine; 2,4-Di(trifluoromethyl)pyridine; Pyridine, 2,4-bis(trifluoromethyl)-; 2,4-Bistrifluoromethylpyridine; 2,4-Bis(trifluoromethyl)pyridine (contains stabilizer); 454-99-9 (CAS RN)
EINECS	Contact for details

Quality Control

Our 2,4-Bis(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. Due to its fluoride/strong alkali chemical property, ensure containers are kept tightly sealed and stored separately from bases and reactive metals.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.