Description

Ethyl 4-Fluorobenzoate is a versatile organic ester building block characterized by its fluorinated aromatic ring. This compound is valued for its role as a key intermediate in the synthesis of more complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by research institutions and industrial manufacturers engaged in the development of active pharmaceutical ingredients (APIs), liquid crystal materials, and advanced organic materials. Its specific structure offers a strategic entry point for introducing fluorine atoms into target molecules, a common strategy to modulate biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of various active pharmaceutical ingredients (APIs), especially those containing fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the fluorine moiety enhances efficacy and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Organic Synthesis & Research: A valuable reagent in academic and industrial R&D for constructing complex organic molecules, including polymers and fine chemicals.
• Flavor & Fragrance Industry: Can be utilized as an intermediate for synthesizing specific aromatic esters.
• Material Science: Acts as a monomer or modifier in the production of specialty polymers and advanced materials.

Basic Information

Product Name	Ethyl 4-Fluorobenzoate
CAS No.	451-46-7
Molecular Formula	C9H9FO2
Molecular Weight	168.16 g/mol
Synonyms	Ethyl p-Fluorobenzoate; 4-Fluorobenzoic Acid Ethyl Ester; Benzoic acid, 4-fluoro-, ethyl ester; p-Fluorobenzoic Acid Ethyl Ester; Ethyl 4-Fluorobenzenecarboxylate; NSC 404080; UNII-9K2F9GQB4I
EINECS	207-200-2

Quality Control

Our Ethyl 4-Fluorobenzoate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including assay (HPLC), identity confirmation (IR, NMR), and impurity profiling, to ensure it meets the high standards required for synthetic applications. We provide full traceability and Certificates of Analysis (COA) are available for every shipment upon request, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%
Density (at 20°C)	~1.15 g/cm³
Refractive Index (n20/D)	~1.495

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.