Description

Methyl Trifluoroacetate is a versatile and highly reactive fluorinated ester. It serves as a critical reagent and building block in advanced organic synthesis, particularly for introducing the trifluoroacetyl group. This compound is essential for manufacturers and R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to enhance molecular properties or create novel compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring trifluoromethyl groups for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the trifluoroacetate moiety contributes to efficacy.
• Peptide Chemistry: Acts as a protecting group reagent for amino acids during peptide synthesis.
• Organic Synthesis Reagent: Employed as a trifluoroacetylating agent for alcohols, amines, and other nucleophiles in fine chemical production.
• Solvent & Reaction Medium: Utilized as a specialty solvent in certain fluorination reactions and electrochemical applications.
• Polymer & Material Science: Serves as a monomer or modifier in the synthesis of fluorinated polymers with unique surface properties.

Basic Information

Product Name	Methyl Trifluoroacetate
CAS No.	431-47-0
Molecular Formula	C3H3F3O2
Molecular Weight	128.05 g/mol
Synonyms	Trifluoroacetic Acid Methyl Ester; Methyl Trifluoroethanoate; Methyl Perfluoroacetate; Methyl Ester of Trifluoroacetic Acid; TFA Methyl Ester; MTAF; Methyl 2,2,2-Trifluoroacetate; Trifluoroacetyl Methyl Ester
EINECS	207-086-4

Quality Control

Our Methyl Trifluoroacetate is manufactured under stringent quality management systems. Each batch is analyzed to ensure high purity and consistency, meeting the rigorous demands of synthesis and production. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and maintain product integrity. Recommended storage temperature is 2-8°C for extended shelf life.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms
Assay (GC)	≥ 99.0%
Water Content (KF)	≤ 0.1%
Refractive Index (n20D)	1.290 - 1.295
Density (20°C)	1.270 - 1.290 g/mL
Boiling Point	~ 40-43°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.