Description

Methyl Dichlorofluoroacetate CAS NO 431-44-7 is a versatile fluorinated organic ester, serving as a critical building block in advanced chemical synthesis. Its unique molecular structure, featuring both fluorine and chlorine substituents, makes it a highly reactive intermediate for introducing fluorinated moieties into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise fluorination to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the preparation of fluorinated active pharmaceutical ingredients (APIs), including protease inhibitors and other bioactive molecules.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, pesticides, and fungicides where the fluorine atom enhances biological activity and environmental stability.
• Fluorinated Material Precursor: Serves as a starting material for synthesizing specialty polymers, liquid crystals, and surface-active agents with unique properties.
• Organic Synthesis Reagent: Employed in nucleophilic substitution and condensation reactions to incorporate the -CHFCl2 or -COOCH3 groups into complex organic frameworks.
• Chemical Research & Development: A valuable tool in medicinal chemistry and material science R&D for exploring new fluorinated compound libraries.

Basic Information

Product Name	Methyl Dichlorofluoroacetate
CAS No.	431-44-7
Molecular Formula	C3H3Cl2FO2
Molecular Weight	160.96 g/mol
Synonyms	Methyl 2,2-dichloro-2-fluoroacetate; Dichlorofluoroacetic Acid Methyl Ester; Fluorodichloroacetic Acid Methyl Ester; Methyl Fluorodichloroacetate; 2,2-Dichloro-2-fluoroacetic Acid Methyl Ester; Acetic acid, 2,2-dichloro-2-fluoro-, methyl ester; Methyl α,α-dichloro-α-fluoroacetate
EINECS	207-088-7

Quality Control

Our Methyl Dichlorofluoroacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical parameters. Our quality commitment ensures the material meets the stringent requirements for use in regulated synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	1.45 - 1.50 g/cm³
Refractive Index (n20D)	1.410 - 1.420

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.