Description

Clomegestone is a synthetic progestogen steroid, identified by CAS NO 424-89-5. This high-purity active pharmaceutical ingredient (API) is valued for its specific hormonal activity and is a critical intermediate in advanced pharmaceutical synthesis. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development and production of specialized hormonal therapies and related compounds.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced progestogen-based active pharmaceutical ingredients (APIs).
• Hormone Research: Used as a reference standard and experimental compound in biochemical and pharmacological research studying progestogen activity and receptor binding.
• Steroid Synthesis: An important precursor in multi-step organic synthesis for creating novel steroid derivatives with potential therapeutic applications.
• Veterinary Medicine Development: Employed in the research and formulation of hormonal treatments for animal health.
• Contraceptive Formulation R&D: Investigated for potential use in the development of new contraceptive and hormone replacement therapies.

Basic Information

Product Name	Clomegestone
CAS No.	424-89-5
Molecular Formula	C22H29ClO4
Molecular Weight	392.92 g/mol
Synonyms	6-Chloro-17-hydroxy-16-methylenepregna-4,6-diene-3,20-dione; 6-Chloro-6-dehydro-16-methylene-17α-acetoxyprogesterone; Chlormadinone Acetate Impurity; Clomegestone Acetate; SH-741; NSC-92336
EINECS	Contact for details

Quality Control

Our Clomegestone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.