Description

Bis(2,2,2-Trifluoroethyl)Amine is a specialized organofluorine compound featuring two trifluoroethyl groups bonded to a central nitrogen atom. This structure imparts unique properties, making it a valuable intermediate for introducing fluorine-containing motifs into target molecules, which can significantly alter their physical, chemical, and biological characteristics. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of fluorinated drug candidates, where the trifluoroethyl group can enhance metabolic stability, lipophilicity, and bioavailability.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides, as fluorination often improves compound activity, selectivity, and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in coordination chemistry and catalysis, particularly for reactions requiring electron-withdrawing groups.
• Advanced Material Precursor: Employed in the development of fluorinated polymers, surfactants, and coatings that require specific surface properties, chemical resistance, or thermal stability.
• Organic Synthesis Reagent: Acts as a versatile reagent for introducing the -NH-CH2CF3 moiety into complex organic frameworks via alkylation or amination reactions.

Basic Information

Product Name	Bis(2,2,2-Trifluoroethyl)Amine
CAS No.	407-01-2
Molecular Formula	C4H5F6N
Molecular Weight	181.08 g/mol
Synonyms	N,N-Bis(2,2,2-trifluoroethyl)amine; Di(2,2,2-trifluoroethyl)amine; 2,2,2-Trifluoro-N-(2,2,2-trifluoroethyl)ethanamine; Bis(trifluoroethyl)amine; N,N-Bis(trifluoroethyl)amine; 1,1,1-Trifluoro-2-(2,2,2-trifluoroethylamino)ethane; (Trifluoroethyl)amine, N,N-bis(trifluoroethyl)-
EINECS	206-971-6

Quality Control

Our Bis(2,2,2-Trifluoroethyl)Amine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and process chemistry. A Certificate of Analysis (COA) detailing specific results for purity, identity, and relevant impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizers. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use and stored at room temperature (15-25°C).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.