Description

2,2,2-Trifluoroethyl Acetate is a versatile fluorinated ester compound valued for its unique combination of high volatility and solvent properties. This makes it a critical intermediate and specialty solvent in advanced chemical synthesis, particularly where the introduction of a trifluoroethoxy moiety is required. It is primarily needed by manufacturers in the pharmaceutical, agrochemical, and electronics industries for applications ranging from active ingredient synthesis to precision cleaning.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), especially those requiring the trifluoroethyl group to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Specialty Solvent: Employed as a high-performance solvent for resins, coatings, and in chemical reactions where a highly volatile, polar aprotic medium is beneficial.
• Electronics Manufacturing: Utilized in precision cleaning formulations and as a process solvent in the production of semiconductors and liquid crystal displays (LCDs).
• Organic Synthesis Reagent: Serves as an acetylating agent and a starting material for the preparation of other trifluoroethyl derivatives in research and development.
• Polymer Modification: Acts as a monomer or modifier in the synthesis of fluorinated polymers, imparting desirable properties like chemical resistance and low surface energy.

Basic Information

Product Name	2,2,2-Trifluoroethyl Acetate
CAS No.	406-95-1
Molecular Formula	C4H5F3O2
Molecular Weight	142.08 g/mol
Synonyms	Acetic Acid 2,2,2-Trifluoroethyl Ester; 2,2,2-Trifluoroethanol Acetate; Trifluoroethyl Acetate; 2,2,2-Trifluoroethyl Ethanoate; TFEA; F3CCH2OCOCH3; Ethanol, 2,2,2-trifluoro-, 1-acetate
EINECS	206-983-7

Quality Control

Our 2,2,2-Trifluoroethyl Acetate is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including GC and NMR analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee compliance with your specific application requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases and oxidizing agents. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature: 2-25°C.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Acidity (as Acetic Acid)	≤ 0.05%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.