Description

3-Isocyanatobenzenesulphonyl Fluoride is a versatile and highly reactive aromatic sulfonyl fluoride derivative containing an isocyanate functional group. This unique bifunctional structure makes it a critical building block for synthesizing advanced materials and specialty chemicals where precise molecular architecture is required. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and polymer industries for creating novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Key synthon for the development of sulfonamide-based drugs, enzyme inhibitors, and targeted covalent inhibitors.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and pesticides with enhanced activity and selectivity.
• Polymer Modification: Serves as a cross-linking agent and functional monomer for engineering high-performance polymers, coatings, and adhesives.
• Chemical Biology Probes: Enables the synthesis of activity-based probes (ABPs) for studying enzyme function and proteomics research.
• Material Science: Building block for advanced materials like metal-organic frameworks (MOFs) and functional surfaces.
• Ligand and Catalyst Development: Used to create novel ligands and organocatalysts for asymmetric synthesis.

Basic Information

Product Name	3-Isocyanatobenzenesulphonyl Fluoride
CAS No.	402-36-8
Molecular Formula	C7H4FNO3S
Molecular Weight	201.17 g/mol
Synonyms	3-Isocyanatobenzenesulfonyl Fluoride; m-Isocyanatobenzenesulfonyl Fluoride; Benzenesulfonyl fluoride, 3-isocyanato-; 3-Isocyanato-1-benzenesulfonyl fluoride; 1-Fluorosulfonyl-3-isocyanatobenzene; 3-Isocyanatophenylsulfonyl Fluoride; Meta-Isocyanatobenzenesulfonyl Fluoride; Isocyanic acid 3-(fluorosulfonyl)phenyl ester
EINECS	Contact for details

Quality Control

Every batch of 3-Isocyanatobenzenesulphonyl Fluoride is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as water, alcohols, amines, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.