Description

Ethyl Iodofluoroacetate is a specialized fluorinated building block of significant interest in advanced synthetic chemistry. Its unique structure, featuring both iodine and fluorine substituents on an acetate ester, makes it a versatile reagent for introducing fluorinated motifs into target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated drug candidates, particularly in medicinal chemistry programs targeting new therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides where the introduction of fluorine atoms can enhance biological activity and stability.
• Fluorine Chemistry Research: A valuable reagent in academic and industrial R&D for studying new fluorination reactions and developing novel synthetic methodologies.
• Material Science Precursor: Serves as a starting material for synthesizing specialized fluorinated polymers or surface-modifying agents with unique properties.
• Radiolabeling Studies: The iodine moiety provides potential pathways for creating radiolabeled tracers for imaging or metabolic studies.

Basic Information

Product Name	Ethyl Iodofluoroacetate
CAS No.	401-58-1
Molecular Formula	C4H6FIO2
Molecular Weight	231.99 g/mol
Synonyms	Ethyl 2-iodo-2-fluoroacetate; 2-Fluoro-2-iodoacetic Acid Ethyl Ester; Iodofluoroacetic Acid Ethyl Ester; Ethyl α-iodo-α-fluoroacetate; Acetic acid, 2-iodo-2-fluoro-, ethyl ester; Ethyl (iodofluoro)acetate; IFAE; Ethyl 2-fluoro-2-iodoacetate
EINECS	Contact for details

Quality Control

Our Ethyl Iodofluoroacetate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques to confirm identity and quantify purity. A comprehensive Certificate of Analysis (COA) detailing specific test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.