Description

1H-Pyrrolo[2,3-B]Pyridine, 5-Methoxy-1-(Phenylsulfonyl)- is a high-purity, advanced pharmaceutical intermediate belonging to the pyrrolopyridine class of heterocyclic compounds. This compound is of significant commercial importance as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in oncology and antiviral research. It is primarily utilized by pharmaceutical R&D laboratories, contract development and manufacturing organizations (CDMOs), and fine chemical suppliers serving the global life sciences industry.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Oncology Research: Serves as a core scaffold for developing small molecule inhibitors targeting specific cancer pathways.
• Antiviral Drug Development: Used in the research and production of compounds with potential activity against various viruses.
• Chemical Biology & Proteomics: Employed as a molecular probe or tag in studying protein-ligand interactions and cellular processes.
• Agrochemical Research: Potential application as an intermediate in the development of new crop protection agents with specific modes of action.
• Material Science: Exploration of its use in creating organic electronic materials due to its conjugated heterocyclic structure.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 5-Methoxy-1-(Phenylsulfonyl)-
CAS No.	397842-89-6
Molecular Formula	C14H12N2O3S
Molecular Weight	288.32 g/mol
Synonyms	5-Methoxy-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1-(Phenylsulfonyl)-5-methoxy-1H-pyrrolo[2,3-b]pyridine; 5-Methoxy-1-tosyl-1H-pyrrolo[2,3-b]pyridine (common); 1H-Pyrrolo[2,3-b]pyridine, 5-methoxy-1-(phenylsulfonyl)-; 397842-89-6; 5-Methoxy-1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1-Benzenesulfonyl-5-methoxy-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine, 5-Methoxy-1-(Phenylsulfonyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for demanding pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.