Description

1,2,3,6-Tetrahydro-Pyridin-3-Ol Hydrochloride is a versatile heterocyclic building block and chiral intermediate of significant interest in advanced organic synthesis. Its value lies in its functionalized piperidine scaffold, which is a privileged structure found in numerous biologically active molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the construction of complex molecules, including potential drug candidates and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of central nervous system (CNS) active drugs, receptor modulators, and other therapeutic agents.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and plant growth regulators that require functionalized piperidine motifs.
• Chemical Research: Serves as a versatile building block in academic and industrial laboratories for exploring new synthetic methodologies and creating compound libraries.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and catalysts.
• Ligand and Catalyst Development: The hydroxyl and amine functionalities make it a candidate for developing chiral ligands and organocatalysts for asymmetric synthesis.

Basic Information

Product Name	1,2,3,6-Tetrahydro-Pyridin-3-Ol Hydrochloride
CAS No.	396730-55-5
Molecular Formula	C5H10ClNO
Molecular Weight	135.59 g/mol
Synonyms	3-Hydroxy-1,2,3,6-tetrahydropyridine hydrochloride; 3-Piperidinol, 1,2,3,6-tetrahydro-, hydrochloride; 1,2,3,6-Tetrahydro-3-pyridinol hydrochloride; 3-Hydroxy-3,4,5,6-tetrahydropyridine hydrochloride; 3-Hydroxytetrahydropyridine HCl; Tetrahydropyridin-3-ol HCl; 3-Piperidinol hydrochloride (partially saturated)
EINECS	Contact for details

Quality Control

Our 1,2,3,6-Tetrahydro-Pyridin-3-Ol Hydrochloride is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, chiral purity (if applicable), and impurity profiles. Our quality systems are designed to support cGMP compliance for pharmaceutical applications, and we can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.