Description

Carbamic Acid, n-[2-Iodo-6-(Trifluoromethoxy)Phenyl]-, Ethyl Ester is a specialized organoiodine building block featuring a trifluoromethoxy substituent. This compound is valued for its unique molecular architecture, which combines halogen and fluorine-containing groups to impart specific electronic and steric properties in advanced synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the construction of complex molecules, particularly in medicinal chemistry programs targeting novel bioactive agents.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs), especially for candidates requiring halogenated aromatic systems.
• Agrochemical Synthesis: Used in the discovery and production of advanced crop protection agents, where the iodine and trifluoromethoxy groups can enhance biological activity and environmental stability.
• Material Science Research: Acts as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials with tailored properties.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization to explore novel chemical space and improve drug-like properties.
• Cross-Coupling Reactions: Functions as a competent substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) due to the presence of the iodine atom.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and labeled compounds for biochemical and diagnostic research applications.

Basic Information

Item	Details
Product Name	Carbamic Acid, n-[2-Iodo-6-(Trifluoromethoxy)Phenyl]-, Ethyl Ester
CAS No.	396075-93-7
Molecular Formula	C10H9F3INO3
Molecular Weight	375.09 g/mol
Synonyms	Ethyl N-[2-Iodo-6-(trifluoromethoxy)phenyl]carbamate; 2-Iodo-6-(trifluoromethoxy)phenylcarbamic Acid Ethyl Ester; Ethyl (2-Iodo-6-((trifluoromethoxy)phenyl)carbamate; N-(2-Iodo-6-(trifluoromethoxy)phenyl)carbamic Acid Ethyl Ester; Carbamic acid, N-[2-iodo-6-(trifluoromethoxy)phenyl]-, ethyl ester; 396075-93-7
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, n-[2-Iodo-6-(Trifluoromethoxy)Phenyl]-, Ethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container sealed to minimize moisture absorption and contact with incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.