Description

Isocyano(3-Methoxyphenyl)Methyl-4-Methylphenyl Sulfone is a specialized organic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a versatile isocyanide reagent, enabling the construction of complex heterocyclic and pharmaceutical scaffolds through multicomponent reactions. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for creating novel molecular entities.

Application

• Key intermediate in the synthesis of novel pharmaceutical candidates, particularly for targeted therapies.
• Critical reagent in multicomponent reactions (MCRs) such as the Ugi and Passerini reactions for rapid library generation.
• Building block for the development of functionalized polymers and advanced materials with specific optical or electronic properties.
• Precursor in agrochemical research for creating new active ingredients with enhanced efficacy.
• Used in chemical biology for probe and ligand discovery due to its reactive isocyano group.
• Employed in academic and industrial R&D for methodological studies in synthetic organic chemistry.

Basic Information

Product Name	Isocyano(3-Methoxyphenyl)Methyl-4-Methylphenyl Sulfone
CAS No.	394655-17-5
Molecular Formula	C16H15NO3S
Molecular Weight	301.36 g/mol
Synonyms	4-Methylbenzenesulfonyl(3-methoxyphenyl)acetonitrile N-oxide; 1-Isocyano-1-(3-methoxyphenyl)-4'-methylphenyl sulfone; [(Isocyano)(3-methoxyphenyl)methyl](4-methylphenyl) sulfone; 4-Methyl-α-isocyano-3-methoxybenzenemethanesulfonyl benzene; (3-Methoxyphenyl)(isocyano)(4-methylphenyl)sulfonylmethane; p-Tolyl (3-methoxyphenyl)(isocyano)methyl sulfone
EINECS	Contact for details

Quality Control

Our Isocyano(3-Methoxyphenyl)Methyl-4-Methylphenyl Sulfone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.