Description

Di-m-Toluoyl-D-Tartaric Acid is a high-purity chiral resolving agent and synthetic intermediate. This compound is valued for its ability to separate enantiomers of amines and other basic compounds through diastereomeric salt formation, a critical process in pharmaceutical development. It is essential for research laboratories and production facilities in the pharmaceutical and fine chemical industries requiring precise chiral separation and synthesis.

Application

• Chiral Resolution Agent: For the separation of racemic mixtures of pharmaceutical intermediates and active ingredients.
• Asymmetric Synthesis: As a chiral auxiliary or catalyst in stereoselective organic reactions.
• Pharmaceutical Intermediate: In the synthesis of enantiomerically pure drugs, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Analytical Standard: Used as a reference standard in HPLC and other chromatographic methods for method development and quality control.
• Fine Chemical Synthesis: Building block for complex molecules in agrochemical and specialty chemical research.
• Academic & Industrial R&D: For method development and process chemistry in chiral technology.

Basic Information

Product Name	Di-m-Toluoyl-D-Tartaric Acid
CAS No.	391624-70-7
Molecular Formula	C20H18O8
Molecular Weight	386.35 g/mol
Synonyms	Di-(3-methylbenzoyl)-D-tartaric acid; (2R,3R)-2,3-Bis(3-methylbenzoyloxy)succinic acid; D-Di-m-Toluoyltartaric Acid; D-DMTTA; (R,R)-Di-m-Toluoyl Tartaric Acid; D-(-)-Di-m-Toluoyltartaric Acid; D-3,3'-Dimethylbenzoyl Tartaric Acid
EINECS	Contact for details

Quality Control

Our Di-m-Toluoyl-D-Tartaric Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity assay and identification, to ensure it meets the high standards required for pharmaceutical applications. A Certificate of Analysis (COA) detailing purity, specific rotation, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Specific Rotation [α]D20	-140° to -150° (c=1 in methanol)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.