Description

Di-o-Toluoyl-D-Tartaric Acid is a high-purity chiral resolving agent derived from D-tartaric acid. This compound is critically important for its role in the separation and purification of enantiomers in pharmaceutical and fine chemical synthesis. It is primarily needed by manufacturers in the pharmaceutical industry, as well as by research institutions and companies specializing in advanced chiral chemistry and catalyst development.

Application

• Chiral Resolution Agent: For the separation of racemic mixtures, particularly of amines and other pharmaceutically active compounds.
• Pharmaceutical Intermediate: Used in the asymmetric synthesis of active pharmaceutical ingredients (APIs) requiring high enantiomeric purity.
• Catalyst Ligand Precursor: Serves as a building block for chiral ligands used in asymmetric catalysis.
• Analytical Chemistry: Employed as a chiral selector in High-Performance Liquid Chromatography (HPLC) for analytical method development.
• Fine Chemical Synthesis: Applied in the production of specialty chemicals where stereochemical control is essential.
• Academic & Industrial Research: A key reagent for method development and discovery chemistry in chiral science.

Basic Information

Product Name	Di-o-Toluoyl-D-Tartaric Acid
CAS No.	391624-66-1
Molecular Formula	C22H22O8
Molecular Weight	414.41 g/mol
Synonyms	Di-o-Toluoyl-D-tartaric Acid; (2R,3R)-2,3-Bis(2-methylbenzoyloxy)succinic Acid; D-Di-o-Toluoyltartaric Acid; D-DOT; (R,R)-Di-o-Toluoyltartaric Acid; DOT; D-(-)-Di-o-Toluoyltartaric Acid; (2R,3R)-Di-o-Toluoyltartaric Acid
EINECS	Contact for details

Quality Control

Our Di-o-Toluoyl-D-Tartaric Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the stringent requirements for chiral resolution and synthesis. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.