Description

1-Oxa-6-Azaspiro[2.5]Octa-4,7-Diene-4-Carboxamide(9Ci) is a high-value, specialized heterocyclic building block used in advanced organic synthesis. This compound matters for its unique spirocyclic and unsaturated lactam-oxazine structure, which provides a versatile scaffold for constructing complex molecules in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring complex heterocyclic cores.
• Agrochemical Research: Used as a building block for developing new active ingredients with potential herbicidal, fungicidal, or insecticidal properties.
• Ligand and Catalyst Development: Serves as a sophisticated backbone for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science: Potential monomer or additive for advanced polymers and functional materials due to its rigid, fused-ring structure.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function or biological pathways.
• Academic & Contract Research: Essential for methodological development and exploration of new chemical spaces in university and CRO laboratory settings.

Basic Information

Product Name	1-Oxa-6-Azaspiro[2.5]Octa-4,7-Diene-4-Carboxamide(9Ci)
CAS No.	389795-79-3
Molecular Formula	C7H8N2O2
Molecular Weight	152.15 g/mol
Synonyms	1-Oxa-6-azaspiro[2.5]octa-4,7-diene-4-carboxamide; 4-Carbamoyl-1-oxa-6-azaspiro[2.5]octa-4,7-diene; Spiro[cyclopropane-1,6'-[1,4]oxazino[4,3-a]pyridine]-4'-carboxamide; 389795-79-3; 1-Oxa-6-azaspiro[2.5]octa-4,7-diene-4-carboxylic acid amide; 9CI Index Name; Fused oxazine-pyridine building block
EINECS	Contact for details

Quality Control

Our 1-Oxa-6-Azaspiro[2.5]Octa-4,7-Diene-4-Carboxamide(9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry for identity confirmation. A detailed Certificate of Analysis (COA) is supplied with each batch, and custom synthesis to meet specific purity or packaging requirements is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.