Description

4-Azidobutanol 1-(4-Methylbenzenesulfonate) is a specialized organic building block featuring both an azido group and a tosylate leaving group, making it a versatile intermediate for click chemistry and nucleophilic substitution reactions. This compound is critical for researchers and manufacturers developing advanced materials, bioconjugates, and pharmaceutical candidates. It is particularly valuable in the fields of polymer science, medicinal chemistry, and proteomics for the controlled introduction of functional groups.

Application

• Click Chemistry Reagent: The azide moiety enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation and polymer functionalization.
• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of novel drug candidates, particularly those requiring triazole linkages or modified sugar derivatives.
• Polymer Modification: Used to introduce cross-linking sites or reactive handles into polymer backbones for creating smart materials and hydrogels.
• Bioconjugation Linker: Facilitates the attachment of labels, probes, or therapeutic payloads to proteins, antibodies, and other biomolecules.
• Material Science: Employed in surface functionalization and the development of advanced coatings with specific chemical properties.
• Chemical Biology Probes: Acts as a precursor for activity-based probes used to study enzyme function and metabolic pathways.

Basic Information

Product Name	4-Azidobutanol 1-(4-Methylbenzenesulfonate)
CAS No.	389131-94-6
Molecular Formula	C11H15N3O3S
Molecular Weight	269.32 g/mol
Synonyms	4-Azidobutyl 4-methylbenzenesulfonate; 4-Azidobutyl tosylate; 1-Azido-4-(tosyloxy)butane; Tosyloxyazidobutane; 4-(Tosyloxy)butyl azide; Butanol, 4-azido-, 1-(4-methylbenzenesulfonate); 4-Azido-1-butanol tosylate; 389131-94-6
EINECS	Contact for details

Quality Control

Our 4-Azidobutanol 1-(4-Methylbenzenesulfonate) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.