Description

1,8-Naphthyridine-3-Carboxamide,n-Phenyl-2-(Trifluoromethyl)-(9Ci) is a specialized heterocyclic organic compound featuring a naphthyridine core substituted with a phenylcarboxamide group and a trifluoromethyl moiety. This molecular architecture makes it a valuable advanced pharmaceutical intermediate and a key building block in medicinal chemistry research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly for targets in oncology, neurology, and infectious diseases.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis due to its privileged heterocyclic structure.
• Agrochemical Development: Employed in the research and development of new herbicides, fungicides, or insecticides, leveraging the biological activity of the naphthyridine core.
• Chemical Biology Probe Synthesis: Utilized to create molecular tools for studying biological pathways and target validation.
• Material Science Research: Investigated as a potential building block for organic electronic materials or metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	1,8-Naphthyridine-3-Carboxamide,n-Phenyl-2-(Trifluoromethyl)-(9Ci)
CAS No.	388565-54-6
Molecular Formula	C₁₆H₁₀F₃N₃O
Molecular Weight	317.27 g/mol
Synonyms	N-Phenyl-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide; 2-(Trifluoromethyl)-N-phenyl-1,8-naphthyridine-3-carboxamide; 1,8-Naphthyridine-3-carboxamide, N-phenyl-2-(trifluoromethyl)-; 388565-54-6; N-Phenyl-2-trifluoromethyl-1,8-naphthyridine-3-carboxamide
EINECS	Contact for details

Quality Control

Our 1,8-Naphthyridine-3-Carboxamide,n-Phenyl-2-(Trifluoromethyl)-(9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request. We support development projects with research-grade material and can scale production under controlled, GMP-like conditions for advanced clinical phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.