Description

Texas Red-2-Sulfonamidoethyl Methanethiosulfonate is a reactive, sulfhydryl-specific fluorescent labeling reagent designed for advanced bioconjugation and protein research. This compound matters for researchers and manufacturers who require precise, covalent attachment of the bright Texas Red fluorophore to cysteine residues in proteins, peptides, and other biomolecules. It is primarily needed by professionals in the life sciences, pharmaceutical development, and diagnostic reagent manufacturing sectors for applications in fluorescence microscopy, flow cytometry, and assay development.

Application

• Fluorescent Labeling of Proteins and Antibodies: Covalently attaches the Texas Red fluorophore to thiol groups for creating bright, photostable conjugates used in imaging and detection.
• Bioconjugation for Diagnostic Assays: Used in the development of fluorescent probes and reagents for ELISA, lateral flow assays, and other in vitro diagnostic platforms.
• Live-Cell and Fixed-Cell Imaging: Enables specific labeling of intracellular proteins or surface receptors for fluorescence microscopy and super-resolution imaging studies.
• Flow Cytometry Probe Synthesis: Serves as a key building block for creating custom fluorescent tags for cell sorting and analysis.
• Peptide Tagging and Tracking: Allows for the site-specific modification of synthetic peptides to study protein-protein interactions, localization, and turnover.
• Material Science and Sensor Development: Functionalizes surfaces or nanomaterials with fluorescent markers for biosensing and biointerface research.

Basic Information

Product Name	Texas Red-2-Sulfonamidoethyl Methanethiosulfonate
CAS No.	386229-76-1
Molecular Formula	C27H25N3O8S3
Molecular Weight	623.70 g/mol
Synonyms	Texas Red® maleimide alternative; Texas Red iodoacetamide alternative; Texas Red MTSEA; Sulfosuccinimidyl 6-(Texas Red sulfonamido)hexanoate derivative; 2-((5-(2-(Methanesulfonylthio)ethyl)sulfamoyl)-2-(6-(diethylamino)-3-(diethyliminio)-3H-xanthen-9-yl)benzoyl)amino)acetic acid; Texas Red C2 Maleimide; Reactive Texas Red dye; Thiol-reactive Texas Red probe
EINECS	Contact for details

Quality Control

Our Texas Red-2-Sulfonamidoethyl Methanethiosulfonate is produced under strict quality management protocols to ensure batch-to-batch consistency and high performance for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	Dark red to purple solid or film
Identification (HPLC/UV-Vis)	Conforms
Purity (HPLC)	≥ 90% (typical)
Extinction Coefficient (ε)	~85,000 cm⁻¹M⁻¹ (at λmax)
Solubility	Soluble in DMSO, DMF; sparingly soluble in aqueous buffer
Moisture Content (KF)	< 5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.