Description

2-Chloro-6-Methoxyphenylboronic Acid is a versatile and high-value boronic acid derivative, a key building block in modern synthetic organic chemistry. Its primary value lies in enabling the precise construction of complex molecules through reliable cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in constructing biaryl and heterobiaryl scaffolds common in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific chlorinated methoxy-phenyl structures.
• Material Science Research: Serves as a monomer or building block for creating specialized polymers, ligands for catalysts, and organic electronic materials.
• Cross-Coupling Reactions: Primarily employed in palladium-catalyzed Suzuki-Miyaura couplings to form carbon-carbon bonds with high fidelity and functional group tolerance.
• Chemical Biology & Proteomics: Can be utilized in the development of chemical probes and inhibitors for studying biological pathways and protein function.
• Ligand Synthesis: Acts as a starting material for the preparation of sophisticated bidentate or monodentate ligands used in homogeneous catalysis.

Basic Information

Item	Detail
Product Name	2-Chloro-6-Methoxyphenylboronic Acid
CAS No.	385370-80-9
Molecular Formula	C7H8BClO3
Molecular Weight	186.40 g/mol
Synonyms	(2-Chloro-6-methoxyphenyl)boronic acid; 2-Chloro-6-methoxybenzeneboronic acid; Boronic acid, B-(2-chloro-6-methoxyphenyl)-; 385370-80-9; 2-Chloro-6-methoxy phenyl boronic acid; 2-Methoxy-6-chlorophenylboronic acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Methoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.