Description

1,2-Dioleoyl-Sn-Glycero-3-Phosphoethanolamine-n-(Lissamine Rhodamine B Sulfonyl) is a high-purity, fluorescently labeled phospholipid essential for advanced biomedical research and diagnostic applications. This compound provides a critical tool for the real-time visualization and tracking of lipid membranes, liposomes, and cellular processes due to its bright red fluorescence. It is primarily needed by researchers and developers in pharmaceutical R&D, biotechnology, and diagnostic kit manufacturing for creating fluorescent probes, studying drug delivery mechanisms, and developing advanced cell-based assays.

Application

• Liposome & Nanoparticle Labeling: As a fluorescent tracer in the formulation and stability studies of drug delivery vehicles.
• Membrane Biology Research: For probing lipid bilayer dynamics, membrane fusion, and cellular uptake mechanisms in live-cell imaging.
• Diagnostic Assay Development: Used in the manufacture of fluorescent lateral flow assays and other in-vitro diagnostic (IVD) components.
• Cell Sorting & Flow Cytometry: Incorporation into cell membranes for fluorescence-activated cell sorting (FACS) applications.
• Model Membrane Studies: Key component in creating giant unilamellar vesicles (GUVs) or supported lipid bilayers (SLBs) for biophysical research.
• Pharmaceutical Quality Control: Acts as a process marker during the development and scale-up of lipid-based nanomedicines.

Basic Information

Product Name	1,2-Dioleoyl-Sn-Glycero-3-Phosphoethanolamine-n-(Lissamine Rhodamine B Sulfonyl)
CAS No.	384833-00-5
Molecular Formula	C95H149N4O13PS2
Molecular Weight	~1690.3 g/mol
Synonyms	Rhodamine B-DOPE; Lissamine Rhodamine B Sulfonyl DOPE; Rh-DOPE; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-(lissamine rhodamine B sulfonyl); DOPE-RhB; Fluorescent DOPE; N-(Lissamine Rhodamine B Sulfonyl)-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine; PE-Rhodamine (18:1/18:1)
EINECS	Contact for details

Quality Control

Our 1,2-Dioleoyl-Sn-Glycero-3-Phosphoethanolamine-n-(Lissamine Rhodamine B Sulfonyl) is manufactured under strict quality systems to ensure batch-to-batch consistency for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and fluorescence performance. We adhere to ISO 9001 standards, and our production environment is designed to meet the exacting requirements of the life science industry.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep under an inert atmosphere (argon or nitrogen) to prevent oxidation. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Red to reddish-orange solid or film
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Solubility	Soluble in chloroform, methanol, DMSO
Fluorescence Properties	Ex/Em ~560 nm / ~580 nm (in methanol)
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.